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A High-resolution Method to Assess Cell Multinucleation Using Cytoplasm-localized Fluorescent Probes (CLFP)

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: HUI, Wen (Institute of Materia Medica,Chinese Academy of Medical Sciences & Peking Union Medical College, Bei Jing, China)
  • Co-author(s): Wen Hui: State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Bei Jing, China
    Cui huaqing: State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Bei Jing, China
    Xi meiyang: State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Bei Jing, China
    Xiao qiong: State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Bei Jing, China
    Zhang xiang: State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Bei Jing, China
    Wang xiaojian: State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Bei Jing, China
    Yin dali: State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Bei Jing, China
  • Abstract:

    Backgrounds

    Multinucleated cells have been observed in many diseases including cancer, which is closely related to chromosomal instability although the precise mechanisms remain unclear. Nuclear staining dyes, such as, Giemsa and DAPI, are often used to stain cell nuclei to display the morphologies of cell multinucleation. However, owing to the..

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Last update 4 October 2019

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