Reduced food-effect and enhanced bioavailability of a self-microemulsifying formulation of itraconazole in healthy volunteers
- At: 2007 FIP Congress in Beijing (China)
- Type: Poster
- By: KIM, Chong-Kook (Seoul National University, Seoul, South-Korea)
- Co-author(s): Song, Yun-Kyoung (Korea Food and Drug Administration, SEOUL, South-Korea)
Hong, Ji-Yeon (Seoul National University, SEOUL, South-Korea)
Woo, Jong Soo (Hanmi Pharm Co., Ltd., KYOUNG-GI, South-Korea)
Self-microemulsifying drug delivery systems (SMEDDS) represent a possible alterative to traditional oral formulations of lipophilic compounds. This study was undertaken to compare the oral bioavailability and food-effect of SMEDDS of itraconazole (ITRA-GSMP capsule containing 50 mg as itraconazole), to that of currently marketed formulation.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.