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Reduced food-effect and enhanced bioavailability of a self-microemulsifying formulation of itraconazole in healthy volunteers

  • At: Beijing (China) (2007)
  • Type: Poster
  • By: KIM, Chong-Kook (Seoul National University, Seoul, South-Korea)
  • Co-author(s): Song, Yun-Kyoung (Korea Food and Drug Administration, SEOUL, South-Korea)
    Hong, Ji-Yeon (Seoul National University, SEOUL, South-Korea)
    Woo, Jong Soo (Hanmi Pharm Co., Ltd., KYOUNG-GI, South-Korea)
  • Abstract:

    Self-microemulsifying drug delivery systems (SMEDDS) represent a possible alterative to traditional oral formulations of lipophilic compounds. This study was undertaken to compare the oral bioavailability and food-effect of SMEDDS of itraconazole (ITRA-GSMP capsule containing 50 mg as itraconazole), to that of currently marketed formulation..

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Last update 4 October 2019

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