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Target-mediated drug metabolic characteristics of TCP-1,a novel peptide to diagnose early colorectal cancer

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: FENG, Ru (Institute of Materia Medica Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China)
  • Co-author(s): Bao-Ying Wen: Institute of Materia Medica Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
    Ru Feng: Institute of Materia Medica Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
    Min Huang: Institute of Materia Medica Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
    Yan Wang: Institute of Materia Medica Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
  • Abstract:

    Backgrounds

    A nine cyclic peptide (TCP-1) showed an excellent specificity to colorectal cancer with diameter as small as 2 mm in our previous work.

    Aims

    To study the target-mediated metabolic characteristics and the specificity to colorectal cancer (CRC) of the new peptide TCP-1. 

    Methods

    Pharmacokinetics of TCP-1 in both mice and tumor-bearing mice

    ..

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Last update 4 October 2019

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