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Urate transporter ABCG2-related drug-drug interaction risks during febuxostat medication

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: MIYATA, Hiroshi (The University of Tokyo Hospital, Tokyo, Japan)
  • Co-author(s): Hiroshi Miyata: Department of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan
    Tappei Takada: Department of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan
    Yu Toyoda: Department of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan
    Hirotaka Matsuo: Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Saitama, Japan
    Kimiyoshi Ichida: Department of Pathophysiology, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
    Hiroshi Suzuki: Department of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan
  • Abstract:

    Backgrounds

    ABCG2 is a regulator of the pharmacokinetics of several kinds of drugs and serum uric acid (SUA) levels in humans. This transporter is expressed in many tissues, such as the intestine.

    Aims

    Despite the pharmacological and physiological importance of this transporter, there have been no clinically available modulators of ABCG2 function.

    ..

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Last update 4 October 2019

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