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Changes in the pharmacokinetics of fluvastatin, atorvastatin, and simvastatin but not of rosuvastatin and pravastatin in collagen-induced arthritis rats

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: LIN, Chun-Jung (National Taiwan University, School of Pharmacy, Taipei, China Taiwan)
  • Co-author(s): Chun-Han Lin: School of Pharmacy, National Taiwan University, Taipei, Taiwan, Province of China
    Ke-Wei Hsu: School of Pharmacy, National Taiwan University, Taipei, Taiwan, Province of China
    Chia-Hao Chen: School of Pharmacy, National Taiwan University, Taipei, Taiwan, Province of China
    Yow-Shieng Uang: School of Pharmacy, National Taiwan University, Taipei, Taiwan, Province of China
    Chun-Jung Lin: School of Pharmacy, National Taiwan University, Taipei, Taiwan, Province of China
  • Abstract:

    Backgrounds

    The elevated systemic levels of cytokines in rheumatoid arthritis (RA) can change the expression of metabolic enzymes and transporters. Statins are lipid-lowering agents frequently used in RA patients with concurrent cardiovascular diseases. 

    Aims

    The objective of the present study was to investigate the impacts of RA on the

    ..

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Last update 4 October 2019

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