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Pharmacokinetics and efficacy of Decitabine in restoration of RIP3 for potential therapeutic target for cancer

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: KIM, You-Sun (Ajou University School of Medicine, Biochemistry, Suwon, Korea, Republic Of)
  • Co-author(s): You-Sun Kim: Biochemistry, Ajou University School of Medicine, Suwon, Korea, Republic Of
  • Abstract:

    Backgrounds

    Receptor-interacting protein kinase-3 (RIP3, or RIPK3) is an essential part of the cellular machinery that executes the programmed, or “regulated”, necrotic cell death pathway. Recently, we found that RIP3 expression is often silenced in cancer cells due to genomic methylation near its transcriptional start site and RIP3 expression is..

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Last update 4 October 2019

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