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Analysis of Simultaneous 6-mercaptopurine and Its Metabolites in Dried Blood Spot Using LC-MS/MS: Application of The Method to Support Therapeutic Drug Monitoring

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: HARAHAP, Yahdiana (Universitas Indonesia, Faculty of Pharmacy, Depok, Indonesia)
  • Co-author(s): Yahdiana Harahap: Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia
    Supandi supandi: Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia
    Harmita harmita: Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia
    Rizka Andalusia: Research and Development, Dharmais Cancer Hospital, Jakarta, Indonesia
    Marlina Ika: Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia
    Nurul Azizah: Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia
  • Abstract:

    Backgrounds

    6-Mercaptopurine (6-MP) is an antineoplastics drug which has narrow therapeutic index, therefore therapeutic drug monitoring is needed to be done. Dried blood spot (DBS) bio sampling method application for 6-Mercaptopurine on childhood Acute Lymphocytic Leukemia (ALL) provides comfort compared with venipuncture. However due to small..

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Last update 4 October 2019

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