Menu
  • Join
  • Login
  • Contact
 

Search abstracts / presentations


How can modelling ensure enough exposure in SAD? – a case study of administration optimization

  • In: Poster Presentation
  • At: Stockholm (Sweden) (2017)
  • Type: Poster
  • Poster code: P-A-068-Monday
  • By: CARLERT, Sara (AstraZeneca, Pharmaceutical Sciences, Mölndal, Sweden)
  • Co-author(s): Sara Carlert: Pharmaceutical Sciences, AstraZeneca, Mölndal, Sweden
    Christer Tannergren: Pharmaceutical Technology and Development, AstraZeneca, Mölndal, Sweden
  • Abstract:

    Backgrounds

    Escalating single dose studies of AZ1 showed limitations in exposure above doses of 200 mg that were likely solubility related, which could potentially jeopardize the future clinical study plan. Time delays for more than a couple of weeks were not permitted, which excluded reformulation of the drug.

    Aims

    The challenge was to create a new

    ..

  • The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress. Please login
Last update 28 September 2023

FIP Congresses