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Rational design of highly efficient cocaine hydrolases for therapeutic treatment of cocaine addiction and overdose

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: ZHAN, Chang-Guo Zhan (University of Kentucky, Department of Pharmaceutical Sciences, Lexington, United States)
  • Co-author(s): Fang Zheng: Department of Pharmaceutical Sciences , University of Kentucky, Lexington, United States
    Chang-Guo Zhan: Department of Pharmaceutical Sciences , University of Kentucky, Lexington, United States
  • Abstract:

    Backgrounds

    Cocaine is a widely abused drug without an FDA-approved medication specific for cocaine addiction or overdose. Nevertheless, it has been recognized that an ideal anti-cocaine medication would accelerate cocaine metabolism producing biologically inactive metabolites.

    Aims

    This study aimed to design and discover highly efficient

    ..

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Last update 4 October 2019

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