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Predicting of biological targets and admet properties of synthesized hydroxyurea derivatives

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: JADRIJEVIC-MLADAR TAKAC, Milena (Faculty of Pharmacy and Biochemistry, University of Zagreb, Department of Medicinal Chemistry, Zagreb, Croatia)
  • Co-author(s): Milena Jadrijevic-Mladar Takac: Department of Medicinal Chemistry, Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia
    Vedran Takac: Department of Pharmacy, Health Institution Stefanic Pharmacies, Zagreb, Croatia
  • Abstract:

    Backgrounds

    A diverse cyclic and acyclic hydroxyurea derivatives were synthesized and tested on different biological acivities, i.e., the cell viability on human acute monocytic leukemia THP-1 and human acute T cell leukemia Jurkat cell lines, as well as on antibacterial activity against three E. coli strains, i.e., a strain susceptible to..

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Last update 4 October 2019

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