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Synthesis of New Benzofuran Derivatives as DNA Intercalating Small Molecules

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: AL-DUHAIDAHAWI, Dunya (Kufa University, Pharmaceutical Chemistry, AL-Najaf, Iraq)
  • Co-author(s): Dunya AL-Duhaidahawi: Pharmaceutical Chemistry, Kufa University, AL-Najaf, Iraq
    Kawkab Saour: Pharmaceutical Chemistry, Baghdad University, Baghdad, Iraq
  • Abstract:

    Backgrounds

    It has been shown that the guanine-rich telomere overhang can extend the G-overhang and thus confer infinite proliferative capacity on cells. The G-rich telomere overhang can overlap into G-quadruplexes, rendering them resistant to extension by telomerase.  In this study, we report novel compounds as Biaryl, polyamide compounds with

    ..

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Last update 4 October 2019

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