intracellular environment-responsive lipid like material as a multi-nanoDDS platform
- At: 2017 FIP Congress in Stockholm (Sweden)
- Type: Presentation
- By: AKITA, Hidetaka (Chiba, Japan)
- Co-author(s): Hidetaka Akita: Graduate School of Pharmaceutical Sciences, Chiba Universitry, Chiba, Japan
While the gene therapy approach has faced technical and/or regulatory impediments, a large number of clinical trials are still ongoing worldwide. Gene expression efficacy is rate-limited by the multiple processes (i.e. cellular uptake, endosomal escape, cytoplasmic transport and nuclear delivery). Adequate design to overcome these.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.