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intracellular environment-responsive lipid like material as a multi-nanoDDS platform

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Presentation
  • By: AKITA, Hidetaka (Chiba, Japan)
  • Co-author(s): Hidetaka Akita: Graduate School of Pharmaceutical Sciences, Chiba Universitry, Chiba, Japan
  • Abstract:

    Backgrounds

    While the gene therapy approach has faced technical and/or regulatory impediments, a large number of clinical trials are still ongoing worldwide. Gene expression efficacy is rate-limited by the multiple processes (i.e. cellular uptake, endosomal escape, cytoplasmic transport and nuclear delivery). Adequate design to overcome these

    ..

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Last update 4 October 2019

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