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Unravelling the cause of the type 2 diabetes epidemic in South Asians: role for the endocannabinoid system?

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Presentation
  • By: KANTAE, Vasudev (University of Leiden, LACDR, Leiden, Netherlands)
  • Co-author(s): Vasudev Kantae: LACDR, University of Leiden, Leiden, Netherlands
    Kimberly J. Nahon: Endocrinology, LUMC, Leiden, Netherlands;Einthoven Laboratory for Experimental Vascular Medicine, LUMC, Leiden, Netherlands
    Maaike Straat: Endocrinology, LUMC, Leiden, Netherlands;Einthoven Laboratory for Experimental Vascular Medicine, LUMC, Leiden, Netherlands
    Leontine E.H. Bakker: Endocrinology, LUMC, Leiden, Netherlands;Einthoven Laboratory for Experimental Vascular Medicine, LUMC, Leiden, Netherlands
    Amy C Harms: LACDR, University of Leiden, Leiden, Netherlands
    Mario Van Der Stelt: LIC, University of Leiden, Leiden, Netherlands
    Mariëtte R. Boon: Endocrinology, LUMC, Leiden, Netherlands;Einthoven Laboratory for Experimental Vascular Medicine, LUMC, Leiden, Netherlands
    Ingrid M. Jazet: Endocrinology, LUMC, Leiden, Netherlands;Einthoven Laboratory for Experimental Vascular Medicine, LUMC, Leiden, Netherlands
    Thomas Hankemeier: LACDR, University of Leiden, Leiden, Netherlands
    Patrick C. N. Rensen: Endocrinology, LUMC, Leiden, Netherlands;Einthoven Laboratory for Experimental Vascular Medicine, LUMC, Leiden, Netherlands
  • Abstract:

    Backgrounds

    South Asians have a higher risk to develop obesity and related disorders compared to white Caucasians. This may in part be due to their lower resting energy expenditure (REE) which coincides with less energy-combusting brown adipose tissue (BAT). Since blockade of endocannabinoid signaling increases BAT activity and over-activation of

    ..

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Last update 4 October 2019

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