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The role of TLR4 in the gut-brain axis in Parkinson’s disease: a translational study from man to mice.

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Presentation
  • By: PEREZ PARDO, Paula (Utrecht University, Pharmacology, Utrecht, Netherlands)
  • Co-author(s): Paula Perez Pardo: Pharmacology, Utrecht University, Utrecht, Netherlands
    Hemraj B Dodiya: Medicine, Rush University Medical center, Chicago, United States
    Christopher B Forsyth: Medicine, Rush University Medical center, Chicago, United States
    Johan Garssen: Pharmacology, Utrecht University, Utrecht, Netherlands
    Ali Keshavarzian: Medicine, Rush University Medical center, Chicago, United States
    Aletta D Kraneveld: Pharmacology, Utrecht University, Utrecht, Netherlands
  • Abstract:

    Backgrounds

    Recent evidence suggesting an important role of gut dysfunction in brain disorders has opened up new directions to explore the possible role of the gut-brain axis in neurodegenerative disorders. 

    Aims

    Given the prominence of colonic dysfunction in Parkinson’s disease patients (PD), we propose that intestinal dysfunction could

    ..

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Last update 4 October 2019

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