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Determination of tiopronin in human plasma by liquid chromatography coupled with tandem mass spectrometry

  • At: 2007 FIP Congress in Beijing (China)
  • Type: Poster
  • By: ZHENG, Heng (Tongji Hospital, Tongji Medical College, Wuhan, China)
  • Co-author(s): Chen, Yali (Tongji Hospital, Tongji Medical College, WUHAN, China)
    Tu, Ning (Tongji Hospital, Tongji Medical College, WUHAN, China)
  • Abstract:

    A liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) method for determination of tiopronin in human plasma using fudosteine as internal standard (IS) was established. Plasma samples was precipitated with methanol : 10μl IS (25μg/ml) solution and 10μl (+/-)-1,4-Dithio-D-threitol(3mg/ml) and 10μl L-Cysteine..

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Last update 4 October 2019

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