Metabolic stability studies of drugs and potential drug candidates supported by LC-MS-based analytical approach
- At: 2016 FIP Congress in Buenos Aires (Argentina)
- Type: Poster
- By: BąCZEK, Tomasz (Medical University of Gdańsk, Department of Pharmaceutical Chemistry, Gdańsk, Poland)
- Co-author(s): Tomasz Bączek:|Mariusz Belka:Department of Pharmaceutical Chemistry,Medical University of Gdansk,Gdansk,Poland|Szymon Ulenberg:Department of Pharmaceutical Chemistry,Medical University of Gdansk,Gdansk,Poland
Drug metabolism is a major determinant governing both pharmacokinetics and clinical response and a great deal of efforts is directed to assess key metabolic parameters in early stages of drug development. A large number of drug candidates have undesirable properties, including low metabolic stability that could result in poor bioavailability or.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.