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Metabolic stability studies of drugs and potential drug candidates supported by LC-MS-based analytical approach

  • At: 2016 FIP Congress in Buenos Aires (Argentina)
  • Type: Poster
  • By: BąCZEK, Tomasz (Medical University of Gdańsk, Department of Pharmaceutical Chemistry, Gdańsk, Poland)
  • Co-author(s): Tomasz Bączek:|Mariusz Belka:Department of Pharmaceutical Chemistry,Medical University of Gdansk,Gdansk,Poland|Szymon Ulenberg:Department of Pharmaceutical Chemistry,Medical University of Gdansk,Gdansk,Poland
  • Abstract:

    Drug metabolism is a major determinant governing both pharmacokinetics and clinical response and a great deal of efforts is directed to assess key metabolic parameters in early stages of drug development. A large number of drug candidates have undesirable properties, including low metabolic stability that could result in poor bioavailability or

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Last update 4 October 2019

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