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Formulation of New Prostate Cancer Molecule, GMC1, for Pre-clinical Studies: Application to Pharmacokinetic Studies

  • At: 2016 FIP Congress in Buenos Aires (Argentina)
  • Type: Poster
  • By: EKPENYONG, Oscar (Texas Southern University, Pharmaceutical Sciences, Houston, United States)
  • Co-author(s): Oscar Ekpenyong:|Marc Cox:Biological Sciences,University of El Paso,El Paso,United States|Huan Xie:Pharmaceutical Sciences,Texas Southern University,Houston,United States
  • Abstract:

    GMC1 directly inhibits FKBP52, a positive regulator of androgen (AR), glucocorticoid, and progesterone receptors activities, making it an attractive for the treatment of castration-resistant prostate cancer.

    We developed and validated an LC/MS/MS method for the quantification of GMC1 in solution, plasma and urine; determined the stability, log P,


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Last update 4 October 2019

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