In vitro evaluation of the cytotoxic, antibacterial and antioxidant properties of selected chitosan derivatives and melittin
- At: 2016 FIP Congress in Buenos Aires (Argentina)
- Type: Poster
- By: DU PLESSIS, Lissinda (North-West University Potchefstrrom Campus, Pharmaceutics, Potchefstroom, South Africa)
- Co-author(s): Lissinda Du Plessis:Pharmaceutics,North-West University Potchefstrrom Campus,Potchefstroom,South Africa|Garmi Jacobs:|Jaco Wentzel:|Sandy van Vuuren:Pharmacy and Pharmacology,Univerisity of the Witwatersrand,Johannesburg,South Africa|Awie Kotze:
There is an increasing need for new functional excipients. We synthesized a wide range of more soluble chitosan derivatives to be used as absorption enhancers. Chitosan derivatives, in combination with melittin, a cationic antimicrobial peptide, has proven synergistic absorption effects in vitro.
In vitro evaluation was performed on HepG2 and.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.