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In vitro evaluation of the cytotoxic, antibacterial and antioxidant properties of selected chitosan derivatives and melittin

  • At: 2016 FIP Congress in Buenos Aires (Argentina)
  • Type: Poster
  • By: DU PLESSIS, Lissinda (North-West University Potchefstrrom Campus, Pharmaceutics, Potchefstroom, South Africa)
  • Co-author(s): Lissinda Du Plessis:Pharmaceutics,North-West University Potchefstrrom Campus,Potchefstroom,South Africa|Garmi Jacobs:|Jaco Wentzel:|Sandy van Vuuren:Pharmacy and Pharmacology,Univerisity of the Witwatersrand,Johannesburg,South Africa|Awie Kotze:
  • Abstract:

    There is an increasing need for new functional excipients. We synthesized  a wide range of more soluble chitosan derivatives to be used as absorption enhancers.  Chitosan derivatives, in combination with melittin, a cationic antimicrobial peptide, has proven synergistic absorption effects in vitro.

    In vitro evaluation was performed on HepG2 and


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Last update 4 October 2019

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