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Preparation of cefuroxime axetil nanoparticles by rapid expansion of supercritical fluid technology

  • At: 2007 FIP Congress in Beijing (China)
  • Type: Poster
  • By: VARSHOSAZ, Jaleh (Isfahan University of Medical Sciences, Isfahan, Iran)
  • Co-author(s): Hassanzadeh, Farshid (Isfahan University of Medical Sciences, ISFAHAN, Iran)
    Mahmoudzadeh, Mahmoud (Isfahan University of Medical Sciences, ISFAHAN, Iran)
    Sadeghi, Amir (Isfahan University of Medical Sciences, ISFAHAN, Iran)
  • Abstract:

    Cefuroxime axetil (CFA) is commonly exists polymorphous of crystalline and amorphous forms, of which the latter exhibits a higher bioavailability. As a poorly water-soluble drug, CFA features a low solubility and dissolution rate in the gastrointestinal tract, which limits its effective absorption and bioavailability. According to Noyes-Whitney..

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Last update 4 October 2019

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