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Phytocannabinoid ?9-tetrahydrocannabinvarin increase inhibitory neurotransmission in mice cerebellum

  • At: 2007 FIP Congress in Beijing (China)
  • Type: Poster
  • By: MA, Yu-ling (University of Reading, Reading, United Kingdom)
  • Co-author(s): Dennis, I (University of Reading, READING, United Kingdom)
    Weston, S (University of Reading, READING, United Kingdom)
    Whalley, B (University of Reading, READING, United Kingdom)
    Stephens, G (University of Reading, READING, United Kingdom)
  • Abstract:

    G-protein coupled cannabinoid CB1 receptors play a major role in presynaptic inhibition Within the cerebellum. In particular, CB1 is prominently expressed in inhibitory synapses between interneurones and Purkinje cells. We combine single and multi-electrode electrophysiological recording in acute brain slices with GTPγS binding assays in..

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Last update 13 May 2019

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