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Pharmacokinetic Impact of Voriconazole on Immunosuppressors: A systematic Review

  • At: Buenos Aires (Argentina) (2016)
  • Type: Poster
  • By: CHEN, Ken (Peking University Third Hospital, Pharmacy Department, Beijing, China)
  • Co-author(s): Ken Chen:|Yuanyuan Liu:|Shuyao Liang:Pharmacy Department,Peking University Third Hospital,Beijing,China|Fang Liu:Pharmacy Department,Peking University Third Hospital,Beijing,China|Suodi Zhai:Pharmacy Department,Peking University Third Hospital,Beijing,China
  • Abstract:

    US">It is common for transplants to use voriconazole and immunosuppressors concomitantly. Voriconazole could elevate blood concentration of immunosuppressors through CYP3A4. Based on package inserts, dosage of cyclosporine and tacrolimus should be reduced, while sirolimus is contraindicated when concomitantly used with voriconazole.



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Last update 4 October 2019

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