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CYP2C19 Polymorphism and Voriconazole Steady-state Trough Concentrations: A Systematic Review

  • At: Buenos Aires (Argentina) (2016)
  • Type: Poster
  • By: CHEN, Ken (Peking University Third Hospital, Pharmacy Department, Beijing, China)
  • Co-author(s): Ken Chen:|Xiaofei Li:Pharmacy Department,Peking University Third Hospital,Beijing,China|Guangyao Li:Pharmacy Department,Peking University Third Hospital,Beijing,China|Huilin Tang:Pharmacy Department,Peking University Third Hospital,Beijing,China|Suodi Zhai:Pharmacy Department,Peking University Third Hospital,Beijing,China
  • Abstract:

    US">Voriconazole is mainly metabolized by CYP2C19 in the liver. The genetic polymorphism of CYP2C19 could result in altered enzyme activity and individual variability of voriconazole.

    US">PubMed, Embase, the Cochrane Library, and three Chinese databases (CNKI, CBM, and WanFang) were searched through Jan 26, 2016. Clinical trials


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Last update 4 October 2019

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