γ-Glutamylcysteine exhibits anti-inflammatory effects via down-regulation of TNF-α and the JNK pathway in acute pancreatitis

• At: 2016 FIP Congress in Buenos Aires (Argentina)
• Type: Presentation
• By: MARTI ANDRES, Pablo (Universidad de Valencia, Department of Physiology, VALENCIA, Spain)
• Co-author(s): Pablo Martí-Andrés:Department of Physiology,Faculty of Pharmacy, University of Valencia,Burjassot, Valencia,Spain|Salvador Pérez:Department of Physiology,Faculty of Pharmacy, University of Valencia,Burjassot, Valencia,Spain|Isabela Finamor:Department of Physiology,Faculty of Pharmacy, University of Valencia,Burjassot, Valencia,Spain|Sergio Rius-Pérez:Department of Physiology,Faculty of Pharmacy, University of Valencia,Burjassot, Valencia,Spain|Raquel Taléns:Department of Pharmacy and Pharmaceutical Technology,Faculty of Pharmacy, University of Valencia,Burjassot, Valencia,Spain|Juan Sastre:Department of Physiology,Faculty of Pharmacy, University of Valencia,Burjassot, Valencia,Spain
  
• Abstract:

  Acute pancreatitis (AP) is an inflammatory process of the pancreatic gland that eventually may lead to severe systemic inflammatory response and death. Cytokines and oxidative stress play a key role in the early stages of the disease. Several studies have described the antioxidant properties of gamma glutamylcysteine (γ-GC), a metabolic precursor

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