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Therapeutic drug monitoring of protease inhibitors in hiv pediatric patients.

  • At: 2007 FIP Congress in Beijing (China)
  • Type: Poster
  • By: CACERES GUIDO, Paulo Arturo (Hospital de Pediatria Garrahan, Buenos Aires, Argentina)
  • Co-author(s): Currás, Verónica (Facultad de Farmacia y Bioquímica (UBA), BUENOS AIRES, Argentina)
    Hocht, Christian (Facultad de Farmacia y Bioquímica (UBA), BUENOS AIRES, Argentina)
    Bologna, Rosa (Hospital de Pediatria Garrahan, BUENOS AIRES, Argentina)
    Mecikovsky, Débora (Hospital de Pediatria Garrahan, BUENOS AIRES, Argentina)
    Rubio, Modesto (Facultad de Farmacia y Bioquímica (UBA), BUENOS AIRES, Argentina)
    Bramuglia, Guillermo (Facultad de Farmacia y Bioquímica (UBA), BUENOS AIRES, Argentina)
  • Abstract:

    Aims: Since antiretroviral (ARV) drugs show high interindividual pharmacokinetic variability, therapeutic drug monitoring (TDM) can be used to optimize dosage regimens, based on achieving plasma levels within a therapeutic range. Several studies have shown a relationship between plasma levels of HIV protease inhibitors (PI) and treatment outcome,..

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Last update 13 May 2019

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