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Effects of daurisoline on early afterdepolarizations induced by dofetilide and on l-type calcium current in isolated ventricular myocytes of rabbit

  • At: 2007 FIP Congress in Beijing (China)
  • Type: Poster
  • By: YANG, Xiaoyan (Tongji Medical College, Wuhan, China)
  • Co-author(s): Liu, Qiang-ni (Tongji Medical College, WUHAN, China)
    Gong, Pei-li (Tongji Medical College, WUHAN, China)
    Zeng, Fan-dian (Tongji Medical College, WUHAN, China)
  • Abstract:

    Aim To study the effects of daurisoline on early afterdepolarizations (EADs) induced by dofetilide (dof) in isolated ventricular myocytes and its effect on ICa-L. Methods Cardiac hypertrophy was induced in rabbits by aortic banding; using standard microelectrode techniques, the effects of dof on action potential duration (APD) and incidence of..

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Last update 13 May 2019

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