Menu
 

Search abstracts


Effects of berberine on the transport of p-gp substrates across caco-2 and l-mdr1 cell monolayers

  • At: 2007 FIP Congress in Beijing (China)
  • Type: Poster
  • By: XIN, Huawen (Wuhan General Hospital, Wuhan, China)
  • Co-author(s): Wu, Xiao-Chun (Wuhan General Hospital, WUHAN, China)
    Li, Qing (Wuhan General Hospital, WUHAN, China)
    Yu, Ai-Rong (Wuhan General Hospital, WUHAN, China)
  • Abstract:

    AIM To investigate the effects of berberine (BBR) on the transport of P-gp substrates including cyclosporine A (CsA) and digoxin across Caco-2 and L-MDR cell monolayers. METHODS Permeability coefficients and transport rates of digoxin and CsA across Caco-2 and L-MDR1 monolayers were measured in the presence of BBR(50µM-5mM). RESULTS The..

  • The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress. Please login
Last update 13 May 2019

FIP Congresses