Isolation, purification and structure determination of new antibiotic sansanmycin with activity against mycobacterium tuberculosis

• At: Beijing (China) (2007)
• Type: Poster
• By: XIE, Yunying (Institute of Medicinal Biotechnology, Beijing, China)
• Co-author(s): Chen, Ruxian (Institute of Medicinal Biotechnology, BEIJING, China)
  Si, Shuyi (Institute of Medicinal Biotechnology, BEIJING, China)
  Xu, Hongzhang (Institute of Medicinal Biotechnology, BEIJING, China)
  
• Abstract:

  OBJECTIVE To isolate and purify the active components from the fermentation broth of Streptomyces sp SS and determine their structures. METHOD Antibiotic activity was determined by a paper-disc agar diffusion assay using Mycobacterium phlei. The active antibiotics were isolated and purified by means of various chromatographies, such as macroporous ..

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