Lx2-32c,a novel taxane with great antitumor efficacy and its mechanism

• In: SIG Pharmaceutical Biotechnology - Posters
• At: Beijing (China) (2007)
• Type: Poster
• Poster code: PB-P-037
• By: WANG, Hongbo (Institute of Materia Medica, Beijing, China)
• Co-author(s): Li, Hongyan (Institute of Materia Medica, BEIJING, China)
  Fang, Weishuo (Institute of Materia Medica, BEIJING, China)
  Ma, Jinbo (Institute of Materia Medica, BEIJING, China)
  Zuo, Mingxin (Institute of Materia Medica, BEIJING, China)
  Liu, Yue (Institute of Materia Medica, BEIJING, China)
  Chen, Xiaoguang (Institute of Materia Medica, BEIJING, China)
  
• Abstract:

  Aim To study the antitumor efficacy and the mechanism of LX2-32C,one novel taxane. Methods The cytotoxic effects of LX2-32C in cell culture was assayed by MTT staining. Cell cycle was analyed by flow cytometry. LX2-32C-induced P53 expression were determined by Western blot methods. The effect of LX2-32C on tubulin morphology in cells was..

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