Dh334, a beta-carboline anti-cancer drug, inhibits the cdk activity of budding yeast
- At: 2007 FIP Congress in Beijing (China)
- Type: Poster
- By: LI, Yan (Institute of Medicinal Biotechnology, Beijing, China)
- Co-author(s): Liang, Feng Shan (Florida State University, TALLAHASSEE, United States of America)
Wang, Yanchang (Florida State University, TALLAHASSEE, United States of America)
Si, Shuyi (Institute of Medicinal Biotechnology, BEIJING, China)
The Î²-carboline alkaloids present in medicinal plants, such as Peganum harmala and Eurycoma longifolia, have recently drawn attention due to their antitumor activities. Further mechanistic studies indicate that Î²-carboline derivatives inhibit DNA topoisomerases and interfere with DNA synthesis. Moreover, some Î²-carboline compounds are.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.