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First synthesisof 12-oxosoladucidine and its derivatives as potential anti-tumor steroidal alkaloids

  • At: 2007 FIP Congress in Beijing (China)
  • Type: Poster
  • By: ZHA, Xiaoming (China Pharmaceutical University, Nanjing, China)
  • Co-author(s): Hou, Yingwei (China Pharmaceutical University, NANJING, China)
    Sun, Hongbin (China Pharmaceutical University, NANJING, China)
    Zhang, Yihua (China Pharmaceutical University, NANJING, China)
  • Abstract:

    First synthesis of 12-oxosoladucidine 4 and its derivatives as potential anti-tumor steroidal alkaloids is described. Starting from hecogenin 5, 4 was prepared in five steps with overall yield 31%. Moreover, 8 derivatives of 4 were synthesized. First synthesis of 12-oxosoladucidine 4 and its derivatives as potential anti-tumor steroidal alkaloids..

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Last update 4 October 2019

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