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Synthesis and evaluation of skin permeation and accumulation profiles of highly lipophilic ketorolac fatty acid esters

  • At: 2007 FIP Congress in Beijing (China)
  • Type: Poster
  • By: YONG, Chul Soon (Yeungnam University, Gyoungsan, South-Korea)
  • Co-author(s): Choi, H. G. (Yeungnam University, GYOUNGSAN, South-Korea)
    Kwak, M. K. (Yeungnam University, GYOUNGSAN, South-Korea)
    Rhee, J. D. (Yeungnam University, GYOUNGSAN, South-Korea)
    Yoo, B. K. (Yeungnam University, GYOUNGSAN, South-Korea)
    Kim, J. A. (Yeungnam University, GYOUNGSAN, South-Korea)
    Lyoo, W. S. (Yeungnam University, GYOUNGSAN, South-Korea)
    Sung, J. H. (Yeungnam University, GYOUNGSAN, South-Korea)
    Newa, M. (Yeungnam University, GYOUNGSAN, South-Korea)
    Bhandari, K. H. (Yeungnam University, GYOUNGSAN, South-Korea)
  • Abstract:

    Aim: Classic penetration retardation methods for topical delivery primarily focus on co-applied chemicals aided alterations in skin permeation profile of penetrants. In many cases, retardation has been achieved by compromising systemic and local toxicities of the retarder(s). In this study, minimal skin accumulation without systemic absorption of..

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Last update 13 May 2019

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