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Ion-pair reversed phase HPLC determination method of metformin hydrochloride in human plasma

  • At: 2007 FIP Congress in Beijing (China)
  • Type: Poster
  • By: LIU, Xiaoying (Guangdong People's Hospital, Guangzhou, China)
  • Co-author(s): Chen, Tiefeng (Guangdong People's Hospital, GUANGZHOU, China)
    Yang, Min (Guangdong People's Hospital, GUANGZHOU, China)
    Yu, Xiyong (Guangdong People's Hospital, GUANGZHOU, China)
  • Abstract:

    Objective: Establish a reversed phase HPLC method of the determination of metfotmin hydrochloride in human plasma. Method: Extracted plasma samples added internal standard and SDS in a single-step with acetonitrile-dichloromethane(1:4,v/v),then evaporated the organic layer to dryness by 50℃ nitrogen stream. Dissolved the residue with water and

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Last update 13 May 2019

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