Bioequivalence of cefditoren in human and pharmacokinetics of absorption in rats

• At: 2007 FIP Congress in Beijing (China)
• Type: Poster
• By: LIU, Kexin (Dalian Medical University, Dalian, China)
• Co-author(s): Liu, qi (Dalian Medical University, DALIAN, China)
  Yao, jihong (Dalian Medical University, DALIAN, China)
  Zhang, qinghao (Dalian Medical University, DALIAN, China)
  
• Abstract:

  Objective：We investigated bioequivalence of cefditoren (CDTR) between cefditoren pivoxil (CDTR-PI) tablet (R) and CDTR-PI granule (T) in 24 healthy male volunteers with a randomized cross over design and examined the biotransformation of CDTR-PI to CDTR in rat intestine. As CDTR is similar to Cephalexin in chemical structure, a challenge is..

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