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Simultaneous stereoselective analysis of venlafaxine and o-desmethylvenlafaxine enantiomers in human plasma by hplc-ms/esi using a vancomycin chiral column

  • At: 2007 FIP Congress in Beijing (China)
  • Type: Poster
  • By: LIU, Wen (Xiangya Second Hospital, Changsha, China)
  • Co-author(s): Wang, Feng (Xiangya Second Hospital, CHANGSHA, China)
    Li, Huande (Xiangya Second Hospital, CHANGSHA, China)
  • Abstract:

    A high-performance liquid chromatography-electrospray ionization mass spectrometry (HPLC-MS/ESI) method for simultaneous stereoselective analysis of venlafaxine(VEN) and its major metabolite O-desmethylvenlafaxine(ODV) enantiomers in human plasma has been developed and validated. Chiral chromatography is performed on the CHRIOBIOTIC V..

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Last update 4 October 2019

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