Frequency of single nucleotide polymorphisms and distinct haplotypes of MDR1 gene in Chinese Han population
- At: 2007 FIP Congress in Beijing (China)
- Type: Poster
- By: XU, Ping (The Second Xiangya Hospital, Changsha, China)
- Co-author(s): Zhang, Bi-Kui (The Second Xiangya Hospital, CHANGSHA, China)
Li, Huan-De (The Second Xiangya Hospital, CHANGSHA, China)
Objective: To investigate the frequencies of SNPs in exon 11 (G1199A), exon 12 (C1236T), exon 21 (G2677T/A) and exon 26 (C3435T) of MDR1gene, and to explore linkage relationship between these SNPs in Chinese Han population. Methods: the frequencies of G1199A, C1236T, G2677T/A and C3435T were evaluated using PCR-RFLP and DNA sequencing in a group.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.