Frequency of single nucleotide polymorphisms and distinct haplotypes of MDR1 gene in Chinese Han population

• In: SIG Pharmaceutical Biotechnology - Posters
• At: Beijing (China) (2007)
• Type: Poster
• Poster code: PB-P-019
• By: XU, Ping (The Second Xiangya Hospital, Changsha, China)
• Co-author(s): Zhang, Bi-Kui (The Second Xiangya Hospital, CHANGSHA, China)
  Li, Huan-De (The Second Xiangya Hospital, CHANGSHA, China)
  
• Abstract:

  Objective: To investigate the frequencies of SNPs in exon 11 (G1199A), exon 12 (C1236T), exon 21 (G2677T/A) and exon 26 (C3435T) of MDR1gene, and to explore linkage relationship between these SNPs in Chinese Han population. Methods: the frequencies of G1199A, C1236T, G2677T/A and C3435T were evaluated using PCR-RFLP and DNA sequencing in a group

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