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Frequency of single nucleotide polymorphisms and distinct haplotypes of MDR1 gene in Chinese Han population

  • At: Beijing (China) (2007)
  • Type: Poster
  • By: XU, Ping (The Second Xiangya Hospital, Changsha, China)
  • Co-author(s): Zhang, Bi-Kui (The Second Xiangya Hospital, CHANGSHA, China)
    Li, Huan-De (The Second Xiangya Hospital, CHANGSHA, China)
  • Abstract:

    Objective: To investigate the frequencies of SNPs in exon 11 (G1199A), exon 12 (C1236T), exon 21 (G2677T/A) and exon 26 (C3435T) of MDR1gene, and to explore linkage relationship between these SNPs in Chinese Han population. Methods: the frequencies of G1199A, C1236T, G2677T/A and C3435T were evaluated using PCR-RFLP and DNA sequencing in a group


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Last update 4 October 2019

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