Discovery of novel cd4 inhibitors as immunosuppressive agents
- At: 2007 FIP Congress in Beijing (China)
- Type: Poster
- By: HE, Xinhua (Institute of Military Medical Sciences, Beijing, China)
- Co-author(s): Zheng, Zhibing (Institute of Military Medical Sciences, BEIJING, China)
Xiao, He (Institute of Military Medical Sciences, BEIJING, China)
Zhang, Han (PLA 301 Hospital, BEIJING, China)
Abstract â€'â€'To optimize the structure of TJU103, we firstly analyzed its pharmic core, and then applied classical drug design rules to modify TJU103 continuously to designed a molecular database which contained two kinds of compounds. The molecule databases were screened by using DOCK4.0 to select molecules for chemical synthesis. 51.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.