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Discovery of novel cd4 inhibitors as immunosuppressive agents

  • At: 2007 FIP Congress in Beijing (China)
  • Type: Poster
  • By: HE, Xinhua (Institute of Military Medical Sciences, Beijing, China)
  • Co-author(s): Zheng, Zhibing (Institute of Military Medical Sciences, BEIJING, China)
    Xiao, He (Institute of Military Medical Sciences, BEIJING, China)
    Zhang, Han (PLA 301 Hospital, BEIJING, China)
  • Abstract:

    Abstract â€'â€'To optimize the structure of TJU103, we firstly analyzed its pharmic core, and then applied classical drug design rules to modify TJU103 continuously to designed a molecular database which contained two kinds of compounds. The molecule databases were screened by using DOCK4.0 to select molecules for chemical synthesis. 51..

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Last update 4 October 2019

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