Rho-kinase pathway contributes to cardiac remodeling in aldosterone/salt-induces hypertensive rats
- At: 2007 FIP Congress in Beijing (China)
- Type: Poster
- By: GUO, Peng (Institute of Materia Medica, Beijing, China)
- Co-author(s): Wang, Xiao Liang (Institute of Materia Medica, BEIJING, China)
Nishiyama, Akira (Kagawa University Medical School, KAGAWA, Japan)
Kohno, Masakazu (Kagawa University Medical School, KAGAWA, Japan)
Recent studies indicate that Rho-kinase is involved in cardiovascular injury. We examined the effects a Rho-kinase inhibitor, fasudil, on the progression of cardiovascular injury in aldosterone/salt-treated uninephrectmized rats. Uninephrectmized rats were treated with 1% NaCl in drinking water (n=6), 1%NaCl + aldosterone (0.75 microg/H, s.c.,.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.