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Rho-kinase pathway contributes to cardiac remodeling in aldosterone/salt-induces hypertensive rats

  • At: Beijing (China) (2007)
  • Type: Poster
  • By: GUO, Peng (Institute of Materia Medica, Beijing, China)
  • Co-author(s): Wang, Xiao Liang (Institute of Materia Medica, BEIJING, China)
    Nishiyama, Akira (Kagawa University Medical School, KAGAWA, Japan)
    Kohno, Masakazu (Kagawa University Medical School, KAGAWA, Japan)
  • Abstract:

    Recent studies indicate that Rho-kinase is involved in cardiovascular injury. We examined the effects a Rho-kinase inhibitor, fasudil, on the progression of cardiovascular injury in aldosterone/salt-treated uninephrectmized rats. Uninephrectmized rats were treated with 1% NaCl in drinking water (n=6), 1%NaCl + aldosterone (0.75 microg/H, s.c.,..

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Last update 4 October 2019

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