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Syudy on the pharmacokinetics and bioequivalence of oxybutynin in 8 dogs after a single and multiple oral administration of osmotic pump tablets

  • At: 2007 FIP Congress in Beijing (China)
  • Type: Poster
  • By: DING, Xueying (Second Military Medical University, Shanghai, China)
  • Co-author(s): GAO, Shen (Second Military Medical University, SHANGHAI, China)
    LIU, Gang-yi (Xuhui Central Hospotial, SHANGHAI, China)
    YU, Chen (Xuhui Central Hospotial, SHANGHAI, China)
  • Abstract:

    AIM To study the pharmacokinetics and bioequivalence of self-prepared osmotic pump tablets(OPT) 、imported OPT and immediate-release(IR) tablets of oxybutynin in dogs.METHODS LC-MS method was developed to detect the plasma drug concentration in 9 dogs. Two one-sided T-test and analysis of variance were performed to evaluate the..

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Last update 4 October 2019

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