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Hydrodynamic considerations for in vitro be methods: diffuison layer thcikness of fenofibrate

  • At: 2007 FIP Congress in Beijing (China)
  • Type: Poster
  • By: SHENG, Jennifer (University of Michigan, Ann Arbor, United States of America)
  • Co-author(s): Sirois, Paul (Eli Lilly and Company, INDIANAPOLIS, United States of America)
    Amidon, Gordon (University of Michigan, ANN ARBOR, United States of America)
  • Abstract:

    The current in vivo bioequivalence (BE) methodology is focusing on comparison of AUC and Cmax through measuring plasma levels. For two drug products containing the same API, their in vivo BE or systematic availability is controlled by their in vivo absorption, which is essentially controlled by in vivo dissolution. The key parameters determining ..

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Last update 4 October 2019

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