Fluorescence derivatization of clarithromycin for high performance liquid chromatographic determination with fluorescence detection

• At: 2007 FIP Congress in Beijing (China)
• Type: Poster
• By: BOONLEANG, Jutima (Prince of Songkla University, Hat-yai, Thailand)
• Abstract:

  Clarithromycin (CAM) is a semisynthetic macrolide antibiotic whose chemical structure has no suitable chromophore for highly sensitive and accurate direct determination. The aim of this study was to derivatize CAM with fluorescence-labeling compounds capable of enhancing the sensitivity of CAM determination. Two fluorescence-labeling compounds..

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