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Evaluation of the usp dissolution test method a for enteric-coated articles by planer laser induced fluorescence

  • At: 2006 FIP Congress in Salvadore (Brazil)
  • Type: Poster
  • By: MILLER, Dave Alan (The University of Texas at Austin, Austin, Texas, United States of America)
  • Co-author(s): Gamba, Mirko (The University of Texas at Austin, AUSTIN, TEXAS, United States of America)
    Sauer, Dorothea (The University of Texas at Austin, AUSTIN, TEXAS, United States of America)
    Purvis, Troy (The University of Texas at Austin, AUSTIN, TEXAS, United States of America)
    Clemens, Noel T. (The University of Texas at Austin, AUSTIN, TEXAS, United States of America)
    Williams III, Robert O. (The University of Texas at Austin, AUSTIN, TEXAS, United States of America)
  • Abstract:

    The USP drug release standard for delayed-release articles Method A was evaluated using Planar Laser Induced Fluorescence (PLIF). Prior authors have suggested that high pH “hot spots” could develop during the buffer medium addition of the Method A enteric test. Additionally, previous studies have shown heterogeneous flow patterns and low-shear ..

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Last update 4 October 2019

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