DEVELOPMENT OF SIMULTANEOUS QUANTIFICATION OF FREE ITRACONAZOLE AND HYDROXY ITRACONAZOLE IN HUMAN PLASMA USING ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY.
- At: 2015 FIP Congress in Düsseldorf (Germany)
- Type: Poster
- By: OYAMA, Nobuhiro (Oita University Hospital, Clinical Pharmacy, Yufu, Japan)
- Co-author(s): Nobuhiro Oyama
Itraconazole (ITCZ) is a common triazole antifungal drug used for the treatment and prevention of fungal infections, and hydroxyl itraconazole (OH-ITCZ) which is a main metabolite of ITCZ, is reported to have antifungal activity. There are several reviews to determine concentrations of ITCZ and OH-ITCZ in human plasma, but free concentrations of.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.