BLOCKING THE L-TYPE CA2+ CHANNELS (CAV1.2) IS THE KEY MECHANISM FOR THE VASCULAR RELAXING EFFECT OF PTERODON SPP. AND ITS ISOLATED DITERPENE METHYL-6Α-ACETOXY-7Β-HYDROXYVOUACAPAN-17Β-OATE
- At: 2015 FIP Congress in Düsseldorf (Germany)
- Type: Poster
- By: ROCHA, Matheus (Federal university of Goias, Pharmacology, Goiânia, Brazil)
- Co-author(s): Matheus lavorenti Rocha
Pterodon pubescens Benth and Pterodon emarginatus Vogel, popularly known as “sucupira”, has ethnopharmacological application which is described as having antispasmodic and relaxant effects. Hence, it was hypothesized that sucupira oil-resin (SOR) could induce smooth muscle relaxation.
Vascular reactivity experiments were performed using rat aortas.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.