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BLOCKING THE L-TYPE CA2+ CHANNELS (CAV1.2) IS THE KEY MECHANISM FOR THE VASCULAR RELAXING EFFECT OF PTERODON SPP. AND ITS ISOLATED DITERPENE METHYL-6Α-ACETOXY-7Β-HYDROXYVOUACAPAN-17Β-OATE

  • At: 2015 FIP Congress in Düsseldorf (Germany)
  • Type: Poster
  • By: ROCHA, Matheus (Federal university of Goias, Pharmacology, Goiânia, Brazil)
  • Co-author(s): Matheus lavorenti Rocha
  • Abstract:

    Pterodon pubescens Benth and Pterodon emarginatus Vogel, popularly known as “sucupira”, has ethnopharmacological application which is described as having antispasmodic and relaxant effects. Hence, it was hypothesized that sucupira oil-resin (SOR) could induce smooth muscle relaxation.

    Vascular reactivity experiments were performed using rat aortas

    ..

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Last update 4 October 2019

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