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FORMULATION DESIGN OF CHRONOPHARMACEUTICAL TABLETS BY THE COMPRESSION-COATING METHOD USING SINGLE-PUNCH AND ROTARY TABLET MACHINES

  • At: 2015 FIP Congress in Düsseldorf (Germany)
  • Type: Poster
  • By: WATANABE, Yoshiteru (Showa Pharmaceutical University, Pharmaceutics and Biopharmaceutics, Tokyo, Japan)
  • Co-author(s): Yoshiteru Watanabe
  • Abstract:

    In 2002, we reported that a novel timed-release tablet, a suitable dosage form for chronopharmacotherapy, can be prepared by the compression-coating method using conventional hydrophilic polymers.

    Aminophylline was chosen as a model drug of chronopharmaceutical tablet.  Low-substitute hydroxypropylcellulose (L-HPC) and cross-povidone (Cross-PVP)

    ..

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Last update 4 October 2019

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