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DESIGN AND OPTIMIZATION OF CLOTRIMAZOLE-HYDROXYPROPYL Β CYCLODEXTRIN BIOADHESIVE VAGINAL TABLETS USING ANACARDIUM OCCIDENTALE GUM BY 32 FACTORIAL DESIGN

  • At: 2015 FIP Congress in Düsseldorf (Germany)
  • Type: Poster
  • By: HANI, Umme (JSS College of Pharmacy, Pharmaceutics, mysore, India)
  • Co-author(s): umme hani
  • Abstract:

    Clotrimazole (CTZ), a BCS class II drug is widely employed in the treatment for vaginal candidiasis. However, attributable to its poor solubility repeated administrations are required to maintain a therapeutic concentration. 

    To increase its aqueous solubility it was complexed with Hydroxypropyl β Cyclodextrin (HPβCD) and formulated as vaginal

    ..

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Last update 4 October 2019

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