IMPROVEMENT IN THE WATER SOLUBILITY OF DRUGS WITH A SOLID DISPERSION SYSTEM BY SPRAY DRYING AND HOT-MELT EXTRUSION WITH USING THE AMPHIPHILIC POLYMER SOLUPLUS®
- At: 2015 FIP Congress in Düsseldorf (Germany)
- Type: Poster
- By: OGAWA, Noriko (Aichi Gakuin University, Pharmaceutical Engineerging, Nagoya, Japan)
- Co-author(s): Noriko Ogawa
In recent years, most of novel developing drugs in the pharmaceutical industry possess strongly hydrophobicity because of their high affinity to the drug potency target. Many problems such as low bioavailability or difficulties in formulation have occurred due to low water solubility. Solid dispersion is a useful technique for improving the.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.