PHYSICAL SOLID-STATE TRANSITION OF INDOMETHACIN IN SUPERCOOLED LIQUID AND STABILISATION OF AMORPHOUS STATE
- At: 2015 FIP Congress in Düsseldorf (Germany)
- Type: Poster
- By: SEMJONOV, Kristian (University of Tartu, Department of Pharmacy, Tartu, Estonia)
- Co-author(s): Kristian Semjonov
Today, 75% of drugs coming out of pipeline are poorly water-soluble. Numerous approaches have been developed to improve the drug water solubility, e.g., s, amorphous solid dispersions (SDs), co-grindingand electrospinning, however with limited success.
The SDs were prepared by QC IND and copolymer/sugar alcohol in different ratios. The molten mass.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.