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PHYSICAL SOLID-STATE TRANSITION OF INDOMETHACIN IN SUPERCOOLED LIQUID AND STABILISATION OF AMORPHOUS STATE

  • At: 2015 FIP Congress in Düsseldorf (Germany)
  • Type: Poster
  • By: SEMJONOV, Kristian (University of Tartu, Department of Pharmacy, Tartu, Estonia)
  • Co-author(s): Kristian Semjonov
  • Abstract:

    Today, 75% of drugs coming out of pipeline are poorly water-soluble. Numerous approaches have been developed to improve the drug water solubility, e.g., s, amorphous solid dispersions (SDs), co-grindingand electrospinning, however with limited success.

    The SDs were prepared by QC IND and copolymer/sugar alcohol in different ratios. The molten mass

    ..

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Last update 4 October 2019

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