PREPARATION AND CHARACTERIZATION OF AVANAFIL NANOCRYSTALS
- At: 2015 FIP Congress in Düsseldorf (Germany)
- Type: Poster
- By: ABOUBAKR, Karim (Faculty of pharmacy, Cairo university, Cairo, Egypt)
- Co-author(s): Karim Aboubakr
Avanafil is a recently EMA-approved PDE5 inhibitor used for treatment of erectile dysfunction.
Combined bottom-up and top-down techniques were used for preparation of 18 nanocrystal formulas in 32.21 full factorial design, where solutions of the drug in dimethylsulphoxide were crystallized by abrupt addition of water as a counter-solvent, then the.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.