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PREPARATION AND CHARACTERIZATION OF AVANAFIL NANOCRYSTALS

  • At: 2015 FIP Congress in Düsseldorf (Germany)
  • Type: Poster
  • By: ABOUBAKR, Karim (Faculty of pharmacy, Cairo university, Cairo, Egypt)
  • Co-author(s): Karim Aboubakr
  • Abstract:

    Avanafil is a recently EMA-approved PDE5 inhibitor used for treatment of erectile dysfunction.

    Combined bottom-up and top-down techniques were used for preparation of 18 nanocrystal formulas in 32.21 full factorial design, where solutions of the drug in dimethylsulphoxide were crystallized by abrupt addition of water as a counter-solvent, then the

    ..

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Last update 4 October 2019

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