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ASYMMETRIC TOTAL SYNTHESIS OF METHYLTERETIFOLIONE B

  • At: 2015 FIP Congress in Düsseldorf (Germany)
  • Type: Poster
  • By: KAINUMA, Mika (Musashino University, Nishitokyo, Japan)
  • Co-author(s): Mika Kainuma
  • Abstract:

    (+)-Methylteretifolione B (1), isolated from Australian Conospermum plants is a monomeric chromenoquinone, related to trimetric anti-HIV conocurvone.  The structure-activity relationship study of natural conocurvone and mono- and polymeric chromenoquinones showed that the trimeric structure is crucial for the anti-HIV activity.

    Diels-Alder approach

    ..

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Last update 4 October 2019

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