DESIGN AND SYNTHESIS OF NEW 2-SUBSTITUTED BENZIMIDAZOLE AS DUAL INHIBITORS FOR C-MET AND VEGFR-2
- At: 2015 FIP Congress in Düsseldorf (Germany)
- Type: Poster
- By: IBRAHIM, Heba (Future University in Egypt ( F U E ), Pharmaceutical Chemistry, Cairo, Egypt)
- Co-author(s): Heba Ahmed Ibrahim
In recent years, some c-Met/VEGFR-2 dual inhibitors have been reported or have entered clinical trials. Most of these tyrosine kinase inhibitors contain various heterocyclic scaffold, so recent developments on 2-substituted benzimidazoles have revealed various heterocycles substituted at 2-position to yield potent anticancer agents.
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