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DESIGN AND SYNTHESIS OF NEW 2-SUBSTITUTED BENZIMIDAZOLE AS DUAL INHIBITORS FOR C-MET AND VEGFR-2

  • At: 2015 FIP Congress in Düsseldorf (Germany)
  • Type: Poster
  • By: IBRAHIM, Heba (Future University in Egypt ( F U E ), Pharmaceutical Chemistry, Cairo, Egypt)
  • Co-author(s): Heba Ahmed Ibrahim
  • Abstract:

     In recent years,  some c-Met/VEGFR-2 dual inhibitors have been reported or have entered clinical trials. Most of these tyrosine kinase inhibitors contain various heterocyclic scaffold, so recent developments on 2-substituted benzimidazoles have revealed various heterocycles substituted at 2-position to yield potent anticancer agents.

     In view of

    ..

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Last update 4 October 2019

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